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Efficacy of an inactivated aqueous vaccine for the control of enzootic pneumonia in pigs infected with Mycoplasma hyopneumoniae
  1. A. Tzivara, DVM1,
  2. S. K. Kritas, DVM, PhD, DiplECPHM1,
  3. A. R. Bourriel, DVM, PhD2,
  4. C. Alexopoulos, DVM, PhD, DiplECPHM3 and
  5. S. C. Kyriakis, DVM, PhD, DiplECPHM4
  1. 1 Clinic of Medicine, University of Thessaly, 43100 Karditsa, Greece
  2. 2 Department of Microbiology, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece
  3. 3 Clinic of Obstetrics and Artificial Insemination, School of Veterinary Medicine, Aristotle University of Thessaloniki 54124 Thessaloniki, Macedonia, Greece
  4. 4 Clinic of Productive Animal Medicine, School of Veterinary Medicine, Aristotle University of Thessaloniki 54124 Thessaloniki, Macedonia, Greece
  1. Correspondence to Dr Kritas at Laboratory of Microbiology and Infectious Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Macedonia, Greece

Abstract

The efficacy of an inactivated aqueous vaccine against Mycoplasma hyopneumoniae was evaluated at two M hyopneumoniae-infected farrow-to-finish commercial farms (A and B) in Greece. In a prospective, randomised double-blind study, two groups on each farm received intramuscular doses of either the vaccine or the adjuvant when they were one and four weeks of age. The pigs were observed daily for clinical signs of disease; morbidity and mortality were recorded; and bodyweight was recorded at intervals. At slaughter, the lungs of the animals were examined and the chest cavities were examined for signs of pleuritis. No adverse reactions to the treatments were observed in any of the pigs. On farm A the vaccinated pigs were on average 6 kg heavier at slaughter, and on farm B they were on average 4 kg heavier; on both farms the average daily gain of the pigs was greater than that of the unvaccinated pigs. The prevalence and severity of enzootic pneumonia in the affected lungs were significantly lower in the vaccinated than in the unvaccinated pigs.

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