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Acquired idiopathic laryngeal paralysis as a prominent feature of generalised neuromuscular disease in 39 dogs
  1. N. D. Jeffery, BVSc, PhD, CertSAO, DSAS(ST), DipECVN, DipECVS, FRCVS1,
  2. C. E. Talbot, MA, VetMB, MRCVS1,
  3. P. M. Smith, BSc, BVM&S, PhD, MRCVS1 and
  4. N. J. Bacon, MA, VetMB, CertVR, CertSAS, DipECVS, MRCVS1
  1. 1Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES

Abstract

A retrospective evaluation of 17 dogs treated surgically for idiopathic acquired laryngeal paralysis demonstrated a marked variability in outcome, with many dogs continuing to exhibit weakness and exercise tolerance. In a subsequent prospective study, 22 consecutive affected dogs were tested for neurological deficits by neurological examination, electrodiagnostic evaluation, and blood analysis to measure thyroxine and thyroid-stimulating hormone and to detect any evidence of myasthenia gravis. Clinical neurological deficits and/or electrodiagnostic abnormalities were found in each case. There was limited evidence that specific neurological deficits were associated with a poor prognosis for full recovery of exercise tolerance. None of the dogs was positive for anti-acetylcholine receptor antibodies, and only three showed evidence of thyroid dysfunction.

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      Footnotes

      • Mr Talbot’s present address is Town and Country Veterinary Group, 5 Rubislaw Park Road, Aberdeen AB15 8BX

      • Mr Bacon’s present address is Dick White Referrals, Station Farm, London Road, Six Mile Bottom, Suffolk CB8 0UH

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