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Diurnal variations in the plasma concentration of parathyroid hormone in dogs
  1. I. López, DVM, PhD1,
  2. E. Aguilera-Tejero, DVM, PhD1,
  3. J. C. Estepa, DVM, PhD1,
  4. S. Bas, DVM1,
  5. R. Mayer-Valor, DVM, PhD1,
  6. A. Jiménez, MD2 and
  7. M. Rodríguez, MD, PhD3
  1. 1Departamento Medicina y Cirugía Animal, Universidad de Córdoba, Campus Rabanales, Ctra Madrid-Cádiz km 396, 14014 Córdoba, Spain
  2. 2Unidad de Investigación, Hospital Universitario Nuestra Señora de Candelaria, Tenerife, Spain
  3. 3Unidad de Investigación and Servicio de Nefrologia, Hospital Universitario Reina Sofía, Córdoba, Spain

Abstract

The plasma concentrations of parathyroid hormone (PTH), ionised calcium (Ca2+), total calcium, albumin and inorganic phosphorus, and the pH were measured in blood samples obtained from nine dogs during a period of 26 hours. The plasma PTH levels fluctuated slightly during the day, by about 20 pg/ml, but there was a distinct peak (42·8 [8·8] pg/ml) at 07.00. Plasma Ca2+ showed a diurnal pattern in which two peaks (increases of 0·03 mmol/l) were observed at 05.00 and 17.00, and the plasma concentration of inorganic phosphorus showed a similar pattern. There were no diurnal changes in total calcium or albumin.

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