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Management of leishmanial osteolytic lesions in a hypothyroid dog by partial tarsal arthrodesis
  1. J. Franch, DVM, PhD,
  2. P. Lafuente, DVM,
  3. M. C. Diaz-Bertrana, DVM, PhD,
  4. A. Munilla, DVM,
  5. I. Durall, DVM, PhD1,
  6. J. Pastor, DVM, PhD and
  7. E. Torrent, DVM2
  1. 1 Department of Surgery
  2. 2 Department of Internal Medicine,Veterinary School, Autonomous University of Barcelona, 08193 Bellaterra, Barcelona, Spain

Abstract

A five-year-old male boxer, previously diagnosed with leishmaniasis and hypothyroidism, had gradually become unable to bear weight on its left hindlimb. Physical examination revealed a left popliteal lymphadenopathy, mild crepitus, and severe swelling of the left tarsal joint, a radiographic examination of which revealed severe bone destruction of the talus and a periosteal reaction of the calcaneus. Laboratory findings and serological tests suggested an active leishmanial infection, and a Leishmania species was identified by direct cytology of a sample from the osteolytic area and by indirect immunohistochemistry of a bone biopsy. The dog's condition improved when it was treated with meglumine antimonate and allopurinol. Because of the large osteolytic area and the increased use of the affected leg, a partial tarsal arthrodesis was performed to prevent a fracture. Five months after the surgery, the osteolytic area had healed completely and the calcaneus periosteal reaction had disappeared.

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