rss
Veterinary Record 154:457-463 doi:10.1136/vr.154.15.457
  • Papers & Articles

Serum antibody titres to canine parvovirus, adenovirus and distemper virus in dogs in the UK which had not been vaccinated for at least three years

  1. N. S. Maxwell, MA, VetMB, CertVR, MRCVS4
  1. 1 Queen's Veterinary School Hospital, Department of Clinical Veterinary Medicine, Madingley Road, Cambridge CB3 OES
  2. 2 Canine Infectious Diseases Research Unit, Department of Veterinary Pathology, University of Glasgow Veterinary School, Glasgow G61 1QH
  3. 3 Penhales House, Ruscombe Lane, Ruscombe, Reading RG10 9JN
  4. 4 Lady Margaret House, St Anne's Road, Prestwich, Manchester M25 8LF
  1. Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa

Abstract

Antibody titres to canine distemper (CDV), canine parvovirus (cpv) and canine adenovirus (cAV) were measured in 144 adult dogs that had not been vaccinated for between three and 15 years. Protective antibodies to cpv were present in 95 per cent of the population, to CDV in 71.5 per cent and to CAV in 82 per cent. The prevalence of protective titres did not decrease with increasing time interval from the last vaccination for any of the three diseases studied. Booster vaccination increased the dogs CAV titres. For comparative purposes, 199 puppies were sampled at the time of their first and second vaccination. In the case of cpv and cAv a significantly higher proportion of the adult dogs were protected than of the puppies immediately after they were vaccinated. Natural cpv boosting was strongly suspected because the dogs had significantly higher titres three years after their primary vaccination than two weeks after it and three unvaccinated dogs had acquired protective antibody levels uneventfully. There was no evidence of natural exposure to CDV.

    Sign up for job alerts

    Vet Record Careers features a comprehensive database of vet jobs.
    Browse for your next job, or set personalised job alerts so you hear about vacancies as soon as they go online.
    Find out more at Vet Record Careers

    Free Sample Issue

    This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of the Veterinary Record.
    View free sample issue >>

    Navigate This Article