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Use of nuclear scintigraphy with 99mTc- HMPAO-labelled leucocytes to assess small intestinal malabsorption in 17 horses
  1. N. J. Menzies-Gow, MA, VetMB, CertEM(IntMed), MRCVS1,
  2. R. Weller, DrMedVet, MRCVS1,
  3. I. M. Bowen, BVetMed, CertVA, CertEM(IntMed), MRCVS1,
  4. K. T. T. Corley, BSc, BVM&S, MS, PhD, DipACVIM, DipACVECC, MRCVS1,
  5. L. Livesey, BVM&S, CertEM(IntMed), MRCVS1,
  6. M. Weaver, BVMS, PhD, DVR, MRCVS2 and
  7. C. M. Marr, BVMS, MVM, PhD, DEIM, DipECEIM, MRCVS1
  1. 1 Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms AL9 7TA
  2. 2 Department of Clinical Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OJG

Abstract

The diagnostic and prognostic value of nuclear scintigraphy with technetium-99m-labelled hexamethylpropyleneamine oxime-labelled leucocytes was assessed in 17 horses with weight loss due to gastrointestinal malabsorption by comparing the results with the results obtained from 13 normal control horses. Intestinal uptake of activity was detected in 12 of the 17 cases but none of the control horses. The technique was therefore specific for intestinal pathology, but failed to detect some horses that might have had intestinal pathology. No indications of the horses' specific pathology were obtained, and their prognosis or response to treatment could not be predicted.

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