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Studies of serum total immunoglobulin E concentrations in atopic and non-atopic dogs
  1. M. A. Fraser, BVMS, PhD, CertVD, CBiol, MlBiol, MRCVS1,
  2. P. E. McNeil, BVMS, PhD, DiplECVP, MRCVS1 and
  3. G. Gettinby, BSc, DPhil, HonAssocRCVS2
  1. 1 Department of Veterinary Pathology, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 IQH
  2. 2 Statistics and Modelling Science, University of Strathclyde, Glasgow GI IXH
  1. Veterinary Dermatology Referrals, Peebles, Borders EH45 9ND

Abstract

The serum total immunoglobulin E (IgE) concentrations of two groups of atopic dogs and three groups of non-atopic dogs were compared. There was a wide range of concentrations with a high degree of overlap between the groups. The serum total IgE concentrations of a group of 15 non-atopic racing greyhounds were significantly higher than those of all the other groups. Atopic and non-atopic dogs receiving stringent parasite control treatments could not be differentiated on the basis of their serum total IgE concentrations. In the non-atopic dogs there was no correlation between their serum total IgE concentrations and the number of allergen-specific positive results obtained in an ELISA, or between their serum total IgE concentrations and their age.

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