Five chimpanzees at the Limbe Wildlife Centre in Cameroon, of both sexes and between six and eight years of age, were treated with lufenuron at a dose rate of 60 mg/kg bodyweight to control various types of mycotic skin infections. The 409.8 mg tablets were administered by mixing them with milk and avocado. Each animal received two or three treatments three weeks apart. Most of them improved significantly during the two to three weeks after the first treatment, and they had completely recovered two to four months later. All the chimpanzees accepted the medication readily, and no adverse drug reactions were observed either immediately after the treatment or during the subsequent eight to 10 months.