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Aid to the antemortem diagnosis of Fell pony foal syndrome by the analysis of B lymphocytes
  1. G. W. Thomas, BVM&S, PhD, MRCVS1,
  2. S. C. Bell, PhD2,
  3. C. Phythian, BSc2,
  4. P. Taylor, MIBLS2,
  5. D. C. Knottenbelt, BVM&S, DVM&S, MRCVS2 and
  6. S. D. Carter, BSc, PhD, FRCPath1
  1. 1 Department of Veterinary Pathology, University of Liverpool, Liverpool L69 7ZJ
  2. 2 Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Liverpool L69 3BX

Abstract

Fell pony foals are affected by a congenital fatal immunodeficiency that commonly leads to anaemia and lymphopenia. Previous work has shown that the foals' circulating subpopulations of CD4 and CD8 T lymphocytes are unaffected. In this study it was shown that the mean population of B lymphocytes in 10 affected foals was less than 10 per cent of that in normal foals.

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