Article Text

Induction of enzootic pneumonia in pigs by the administration of an aerosol of in vitrocultured Mycoplasma hyopneumoniae
  1. T. Czaja, BAgrSc, MSc1,
  2. A. Kanci, BSc1,
  3. L. C. Lloyd, BVSc, PhD1,
  4. P. F. Markham, BSc, PhD1,
  5. K. G. Whithear, BVSc,PhD, HDA1 and
  6. G. F Browning, BvSc,DipVetClinStud, PhD1
  1. 1 Department of Veterinary Science, Veterinary Preclinical Centre, The University of Melbourne, Cnr Flemington Road and Park Drive, Parkville, Victoria 3010, Australia


The aim of this study was to establish whether enzootic pneumonia could be induced reliably in piglets by administering an aerosolised culture of Mycoplasma hyopneumoniae. Groups of five M hyopneumoniae-free Landrace × Large White piglets weaned at 11 to 14 days of age were exposed to aerosols of in vitro cultures of a virulent strain of M hyopneumoniae. In three separate trials, 14 of 15 pigs exposed to the bacteria developed pneumonia, but pigs exposed to the culture medium alone did not develop the disease. Lung pathology, both gross and histological, indicated acute disease. Ten of the pigs were tested for seroconversion by Western blot and they were all positive. The growth rates of the infected pigs were significantly reduced and the water consumption of the infected groups was also depressed. M hyopneumoniae was recovered from eight of the 15 infected pigs.

Statistics from

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.