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Efficac of moxidectin 2 per cent gel against naturally acquired strongyle infections in horses, with particular reference to larval cyathostomes
  1. K. Bairden, BA, MSc, PhD1,
  2. S. R. Brown2,
  3. J. McGoldrick, BSc2,
  4. L. D. Parker, BSc3 and
  5. P. J. Talty, MVB, MA,MRCVS4
  1. 1 58 Merkland Drive, Rosebank, Kirkintilloch, Glasgow G66 3SF
  2. 2 Department of Veterinary Parasitology, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 1QH
  3. 3 Fort Dodge Animal Health, Southampton S03 4QH
  4. 4 Kiltanon House, Tulla, County Clare, Ireland


The efficacy of moxidectin 2 per cent equine gel against naturally acquired strongyle infections was assessed in 18 ponies which had grazed on contaminated pasture before being housed for eight weeks. Twenty-four hours before the treatment, two randomly selected ponies were euthanased and their worm burdens were determined. Eight of the remaining 16 ponies were treated with moxidectin 2 per cent gel while the other eight were given a placebo gel. Eight weeks later the 16 animals were necropsied and their worm burdens established. A 100 per cent efficacy was recorded against adult and lumenal L4 cyathostomes and adult Strongylus and Triodontophorus species. Digest recoveries of larval cyathostomes indicated a 90.8 per cent (P<0.002) reduction in early L3 and a 99-9 per cent (P<0.001) reduction in developing stages. There was a reduction in faecal egg output of between 96 and 100 per cent in the treated animals compared with the controls.

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