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Serum α-tocopherol concentrations in German shepherd dogs with chronic degenerative radiculomyelopathy
  1. P. E. J. Johnston, BVM&S,PhD, MRCVS1,
  2. I. R. Griffiths, BVMS, PhD,FRCVS1,
  3. K. Knox, BVMS, PhD,MRCVS2 and
  4. G. Gettinby, BSc, DPhil3
  1. 1 Applied Neurobiology Group, Department of Veterinary Clinical Studies, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 1QH
  2. 2 Meadowbank, 102 Crosshill Road, Lennoxtown G66 7HQ
  3. 3 Department of Statistics and Modelling Science, Livingston Tower, University of Strathclyde, 26 Richmond Street, Glasgow GI 1XH


The concentration of serum α-tocopherol was measured in German shepherd dogs with chronic degenerative radiculomyopathy, and in German shepherd dogs and dogs of other breeds unaffected by the condition. The mean concentration was significantly higher in German shepherd dogs with the condition than in other breeds of dog unaffected by it, but it was not significantly higher than in unaffected German shepherd dogs. Estimates of components of variance indicated that the concentration varied more widely in individual affected dogs than in unaffected dogs, irrespective of breed. These results suggest that chronic degenerative radiculomyopathy in German shepherd dogs is unlikely to be due to uncomplicated vitamin E deficiency.

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