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Canine gonadal dysgenesis syndrome: a case of mosaicism (77,XO-78,XX)
  1. A. M. Mayenco-Aguirre, DVM, PhD1,
  2. J. A. Padilla, DVM, PhD2,
  3. J. M. Flores, DVM, PhD1 and
  4. M. A. Daza, DVM1
  1. 1 Department of Animal Pathology II, Faculty of Veterinary Science, Complutense University of Madrid, 28040, Madrid, Spain
  2. 2 Department of Genetics, Faculty ofVeterinary Science, University of Extremadura, 10071, Cáceres, Spain


A toy poodle bitch had an abnormal oestrus cycle and apparently persistent follicles. Hormonal therapy was unsuccessful. The bitch was ovariohysterectomised and gross and histological evaluation of the ovaries and uterus, together with karyotyping, led to a diagnosis of 77,XO-78,XX mosaicism.

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