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Economic benefits of prophylaxis with diclazuril against subclinical coccidiosis in lambs reared indoors
  1. J. P. Alzieu, DVM1,
  2. C. Mage, ITEB2,
  3. L. Maes, DVM3 and
  4. C. De Mûelenaere, DVM3
  1. 1 Veterinary Clinic Les Althéas, 31 rue Maréchal Clauzel, 09100 Pamiers, France
  2. 2 Institut de l'élevage, Ester, 87069 Limoges, France
  3. 3 Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340 Beerse, Belgium


One hundred and twenty weaned male lambs, naturally infected with Eimeria species, were used to assess the economic benefits of the prophylactic administration of diclazuril. They were randomly divided into four groups of 30 lambs on the basis of their bodyweight and output of oocysts. The groups were either left untreated (group 1), treated orally with a simple dose of diclazuril at 1 mg/kg (group 2), with two doses two weeks apart (group 3), or with sulphadimethoxine at 50 mg/kg for five consecutive days (group 4). No clinical signs of coccidiosis were observed in any of the groups. The output of oocysts was significantly reduced on day 7 after treatment in group 2, on days 7, 14 and 28 in group 3 and on days 7 and 14 in group 4. No significant differences were found between the treated and untreated groups for bodyweight, carcase weight and carcase classification. The mean fattening period was shorter for the treated lambs (52 and 55 days) than for the untreated controls (60 days). The average growth rate of the lambs treated twice with diclazuril and with sulphadimethoxine was improved and the feed conversion rates of the lambs treated once or twice with diclazuril were 7 per cent and 16 per cent better than that of the untreated lambs.

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