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Xanthine urolithiasis in a dachshund
  1. T. Flegel, DVM1,1,
  2. R. Freistadt, DVM2 and
  3. W. Haider, DVM3
  1. 1 Department of Veterinary Surgery
  2. 2 Clinic and Outpatient Department for Small Animals
  3. 3 Institute of Veterinary Pathology, School of Veterinary Medicine, Free University, Berlin, Germany


Calculi were located in the kidneys, the ureters and the bladder of a two-year-old male dachshund. The yellow-greenish calculi developed as a result of impaired transformation of xanthine to uric acid resulting in an increased concentration of xanthine in the urine. The cause of the impaired catabolism of xanthine was probably a disorder of the xanthine oxidase enzyme, which catalyses the transformation of xanthine to uric acid.

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  • Dr Flegel's present address is College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA

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