Article Text

Elimination of mucosal cyathostome larvae by five daily treatments with fenbendazole
  1. J. L. Duncan, BVMS, PhD, MRCVS1,
  2. K. Bairden, BA, MSc, PhD2 and
  3. E. M. Abbott, BVMS, PhD, MRCVS3
  1. 1 Department of Veterinary Clinical Studies
  2. 2 Department of Veterinary Parasitology, University of Glasgow Veterinary School, Bearsden Road, Bearsden, Glasgow G61 1AQ
  3. 3 Hoechst Roussel Vet GmbH, Wiesbaden, Germany


The efficacy of five daily treatments with 7.5 mg fenbendazole/kg bodyweight against mucosal cyathostome larvae was evaluated in 20 12- to 24-month-old ponies with naturally acquired cyathostome infections. After three weeks communal grazing on infected pasture and six weeks indoors, one group of 10 ponies were treated. Six weeks later, both groups of ponies were humanely destroyed and their burdens of large intestinal cyathostome worms, including luminal parasites and mucosal larvae, were assessed. In the control animals approximately 7 per cent of the total worm burden was present in the gut lumen and 93 per cent was present as larvae in the large intestinal mucosa. The efficacy of fenbendazole against the luminal cyathostomes was 90.7 per cent (P<0.01). The total numbers of mucosal larvae, recovered after digestion, were reduced by 95.3 per cent (P<0.0005); mucosal late third and fourth stage larvae were reduced by 99.4 per cent (P<0.0001), and early inhibited third stage larvae by 91.5 per cent (P<0.005).

Statistics from

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.