Article Text

Protection of cattle against rinderpest and lumpy skin disease with a recombinant capripoxvirus expressing the fusion protein gene of rinderpest virus
  1. CH Romero,
  2. T Barrett,
  3. RP Kitching,
  4. VM Carn and
  5. DN Black
  1. Institute for Animal Health, Pirbright Laboratory, Woking, Surrey.

Abstract

Cattle were protected against challenge with rinderpest and lumpy skin disease viruses by vaccination with a recombinant capripoxvirus containing the fusion protein (F) gene of rinderpest virus. The minimum protective immunising doses for rinderpest and lumpy skin disease were 5.5 x 10(4) plaque forming units (pfu) and 1.5 x 10(3) pfu, respectively.

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