Article Text

Adrenocortical carcinoma in a 12-year-old mare
  1. JH van der Kolk,
  2. MH Mars and
  3. I van der Gaag
  1. Department of Large Animal Medicine and Nutrition, Veterinary Faculty, Utrecht University, The Netherlands.


A 12-year-old Dutch warmblood mare was examined because it had suffered colic intermittently for a few years and had lost weight in the previous two months. Palpation per rectum revealed a large firm mass in the left sublumbar region; the mass was classified post mortem as an adrenocortical carcinoma. The basal plasma cortisol concentration (at 10.00) of the mare was 94 nmol/litre, within the normal range. As in another case of adrenocortical neoplasm, a functional tumour could not be demonstrated. Only one of the 21 horses with a neoplasm of the pituitary-adrenocortical axis examined by the authors, had the tumour in the adrenal gland.

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