Article Text

A connective tissue defect in two rabbits similar to the Ehlers-Danlos syndrome
  1. RG Harvey,
  2. PJ Brown,
  3. RD Young and
  4. TJ Whitbread
  1. Veterinary Centre, Cheylesmore, Coventry.


A connective tissue disease resembling the human Ehlers-Danlos syndrome is reported in two sibling rabbits about four months old. The clinical signs included skin hyperextensibility and fragility and poor wound healing. There were ultrastructural abnormalities in the structure of the collagen fibrils and in their arrangement in bundles of fibres. Affected rabbits may be a useful laboratory animal model for collagen disorders in human beings.

Statistics from

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.