Article Text

Cephalexin in ponies: a preliminary investigation
  1. P Lees,
  2. SA May,
  3. RE Hooke and
  4. P Silley
  1. Department of Veterinary Basic Sciences, Royal Veterinary College, North Mymms, Hatfield.

Abstract

The administration of a single dose of the antibacterial agent cephalexin intramuscularly to six ponies at a dose rate of 7 mg/kg was well tolerated. No reactions at the injection site were apparent. It was absorbed rapidly and reached a mean peak plasma concentration of 6.77 micrograms/ml after a mean of 1.41 hours; plasma concentrations above 2.0 and 0.5 micrograms/ml were maintained for 3.8 and 9.8 hours, respectively.

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