Article Text

Efficacy of topically administered ivermectin against chorioptic and sarcoptic mange of cattle
  1. D Barth and
  2. JM Preston
  1. Merck Sharp & Dohme Research Laboratories, Lauterbach, West Germany.


The efficacy of topically administered ivermectin against Chorioptes bovis and Sarcoptes scabiei var bovis on cattle was evaluated in five studies involving a total of 68 cattle. Treatment with ivermectin solution at a dose rate of 500 micrograms/kg bodyweight topically once was fully effective against C bovis and S scabiei when applied to healthy skin. Efficacy against S scabiei was impaired when the formulation was applied over areas of severe lesions caused by this parasite, presumably due to reduced absorption of ivermectin.

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