Article Text

First field trial of fox vaccination against rabies using a vaccinia-rabies recombinant virus
  1. PP Pastoret,
  2. B Brochier,
  3. B Languet,
  4. I Thomas,
  5. A Paquot,
  6. B Bauduin,
  7. MP Kieny,
  8. JP Lecocq,
  9. J De Bruyn,
  10. F Costy and
  11. al. et
  1. Department of Virology-Immunology, Faculty of Veterinary Medicine, Brussels, Belgium.

Abstract

A field trial of fox vaccination against rabies using a vaccinia-rabies recombinant virus was carried out in Belgium on October 24, 1987. Each vaccine capsule contained a suspension of 10(8) TCID50 of the recombinant virus and was introduced into a chicken head. Each chicken head contained 150 mg of tetracycline as a marker of uptake. Two hundred and fifty heads were distributed in an area of 6 km2 situated within a military zone. The bait uptake was monitored for 15 days after the distribution. Sixty-three per cent of the chicken heads were taken by wild animals within that period. The trial was controlled according to the rules defined by the World Health Organisation.

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