Article Text

Bovine virus diarrhoea-mucosal disease virus-induced fetopathy in cattle: Efficacy of prophylactic maternal pre-exposure
  1. SJ Duffell,
  2. MW Sharp,
  3. CE Winkler,
  4. S Terlecki,
  5. C Richardson,
  6. JT Done,
  7. PL Roeder and
  8. CN Hebert

Abstract

Maternal immunity was produced in Jersey heifers by exposing them to bovine virus diarrhoea-mucosal disease virus before conception. In the following pregnancy this immunity protected the fetuses from transplacental infection arising from challenge of the dams at 100 days gestation with homologous virus. Unprotected Jersey heifers showed a high incidence of death and fetal intrauterine growth retardation associated with transplacental viral infection. Functional normality of the locomotor system was assessed retrospectively from cine films of each calf after birth, and scored for each of an overlapping series of clinical signs. The progeny of non-immune dams scored significantly lower than calves from the vaccinated heifers.

    Statistics from Altmetric.com

      Request permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.