Quinuronium sulphate was inoculated into splenectomised calves at various times in relation to artificial infection of the calves with Babesia divergens. When the drug was given one day before the parasites it had no effect on the course of the infection. However, when it was given at the time of onset of fever or haemoglobinuria, development of the infection was arrested. Two weeks after therapy, recrudescences of parasites invariably occurred. In the case of animals treated at onset of fever these recrudescences were accompanied by increasing anaemia. Treated animals resisted subsequent challenge but remained as carriers of the parasite.
- British Veterinary Association. All rights reserved.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.